For over a decade, researchers have been tracking the relationship between cholesterol and garlic. In a recent study, Penn State nutrition professor Yu-Yan Yeh summarized a series of experiments to prove garlic’s cholesterol-busting ability. He gave two groups of rats a high-fat diet and supplemented one group with Aged Garlic Extract. The researchers then soaked the garlic in alcohol, which leaches out the chemical compounds and reduces its smell. The researchers also found that cooking garlic slowed blood clotting, and that it had a mild anticoagulant effect.
Research on garlic and cholesterol has shown no effect on blood lipids
While there has been some discussion about the effects of garlic on blood lipids, research has been mixed. One study found that garlic inhibits the synthesis of cholesterol, while another found that it had no effect. A third study concluded that garlic inhibits the synthesis of fatty acids. It is unclear how this is possible, however. This study used cultured rat hepatocytes and used S-allyl cysteine as a test substance.
However, there are some studies that have shown that garlic can lower cholesterol levels. In animal studies, garlic supplementation decreased cholesterol synthesis. The researchers determined that the decrease in cholesterol synthesis was the main cause of garlic’s hypocholesterolemic effect. In one study, garlic extracts reduced plasma cholesterol levels by four to six percent compared to placebo-treated controls. Other studies show that garlic can reduce total cholesterol levels, but not LDL or HDL.
Fresh garlic reduces total cholesterol
According to Dr. Rupali Datta, a clinical nutritionist, garlic may lower total cholesterol by up to 15 mg/dL and lower levels of low-density lipoprotein by 6 mg/dL. This effect appears to be most noticeable when garlic is consumed daily for at least 8 weeks. The effect of garlic does not seem to increase HDL or reduce triglycerides, but it can lower blood pressure and cholesterol levels. Although most studies have used a particular garlic powder, the benefits of garlic appear to be relatively minor.
Many randomized clinical trials have examined the effects of garlic on lipid levels. In one study, garlic reduced total cholesterol levels by nine to 12 percent, although the effect was modest. Other studies have shown inconsistent results, ranging from only four to six percent. While the findings are promising, further research needs to be done to prove that garlic reduces total cholesterol. Further, many studies have emphasized the need for longer studies. It may be more effective to take garlic supplements orally to reduce triglyceride levels.
Allicin inhibits the synthesis of cholesterol
The antioxidants found in garlic, including allicin, can help your body fight against atherosclerosis and cholesterol. In a study, researchers found that garlic inhibits the production of a substance that promotes the formation of atherosclerosis, known as d9-carnitine. The compound inhibits the conversion of d9-carnitine into TMA by a bacterium called E. timonensis.
Allicin, an important component of garlic, has been studied extensively in laboratory settings. It has been shown to inhibit cholesterol synthesis in test tubes, in animal models, and in the human body. This property makes garlic an important medicinal herb for people suffering from heart disease, diabetes, and obesity. Although the benefits of garlic are clear, some researchers are skeptical. There are still questions about the potency of garlic.
Cooked garlic has a mild anticoagulant effect
Fermented garlic inhibited platelet aggregation and granule secretion, indicating that it has a beneficial effect on cardiovascular disorders. Fermented garlic also reduced the level of triglycerides. The effect of fermented garlic was attributed to its ability to inhibit sterol regulatory element binding protein, which is a precursor to platelets.
It’s not clear if raw or cooked garlic has any cardiovascular benefits, but a 2016 investigation of a clinical trial found that it had a favorable effect on cholesterol levels. The findings of the study were based on a meta-analysis of studies conducted on garlic and lemon juice. The study found that one-half to one clove of garlic per day decreased cholesterol levels by around nine percent. While this study was based on preliminary data, long-term trials are necessary to determine the true impact of garlic on cardiovascular health.
Soy milk has a cholesterol-lowering effect
Soy milk has been shown to lower cholesterol levels in a variety of studies. One study enrolled 80 subjects with high cholesterol, who were randomly assigned to drink either soy milk or cow milk. They were measured for total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and fasting blood glucose levels. Phytosterols, which are beneficial plant compounds, were also tested in some studies.
The petitioner provided a literature search covering the years 1980-March 2010. In addition, the Food Directorate of Health Canada updated the literature search to March 2013. A total of 49 references were identified, with multiple comparisons between soy and the control. The evidence is not conclusive, but it is still good news for soy’s heart health. In addition to lowering cholesterol, soy products are high in fiber and low in saturated fat, making them an excellent choice for heart-healthy diets.
Supplements with garlic have no effect
In 2006, a review of dietary supplements using garlic found no evidence that garlic lowers cholesterol levels. The study was conducted by the National Institutes of Health (NIH) and included subjects with moderately high cholesterol. The study subjects were divided into four groups: one received raw garlic, one received Garlicin powdered garlic, the other received Kyolic aged-garlic, and the fourth group received a placebo. In the study, the garlic supplement dosages were two to three times higher than the recommended daily dose.
Earlier research has also shown that garlic may reduce cardiovascular disease risk factors. In a small number of studies, garlic powder was associated with lower LDL cholesterol and total cholesterol levels. It was also associated with a reduction in blood pressure. However, there are inconsistencies between studies, which may be due to variations in the manufacturing processes used to make the supplements. Although some researchers advocate garlic as a natural, healthy food, the Mayo Clinic claims that there is no evidence that taking supplements containing garlic will decrease cholesterol levels.