The benefits of turmeric face masks are undoubtedly worth noting. It absorbs the pollution, dries out pimples and gives your face a healthy glow. The only downside of turmeric is that it staining properties mean it can leave your skin a yellowish color after rinsing it off. While this is not a health hazard, it is worth knowing about the side effects of turmeric on skin.
Curcumin interferes with cell signals that drive growth of head and neck cancer
Curcumin inhibits cell growth and survival in various head and neck cancer cell lines by interfering with molecular pathways involved in cell proliferation. For example, curcumin inhibits the activity of NF-kB and IkK, two cytokines that drive cellular growth. Curcumin also inhibits the nuclear localization of STAT3, a protein overexpressed in various types of head and neck cancer.
Moreover, curcumin inhibits tumor cell invasion and metastasis, two important steps in solid tumor growth. Curcumin inhibits the expression of VEGF, a key angiogenic factor, and reduces its secretion from extracellular organs. It also inhibits the signaling pathway of VEGF and c-Met/PI3K/Akt/mTOR, two additional angiogenic factors.
In addition to its anticancer properties, curcumin also has antioxidant and anti-inflammatory activity, which may help in the treatment of head and neck cancer. It inhibits cancer cell proliferation and metastasis by upregulating lysosomal enzymes and inducing autophagy. It also enhances the effectiveness of existing chemotherapeutics. It inhibits ROS production and activates antioxidant enzymes.
It may cause allergic reactions
There are many side effects of turmeric on skin, including the possibility of allergic reactions. Curcumin, the active component of turmeric, is an anti-inflammatory and inhibits histamine release from mast cells. In animal studies, curcumin inhibited allergic responses in mice, and human studies have shown improvements in nasal airflow and an improved immune response. Curcumin is a common spice used in cooking, and it can also be taken as a pill.
Although a small number of cases of allergic contact dermatitis have been reported, it is rare. Most of the time, an allergic reaction is not caused by turmeric itself, but by a different substance. It is best to consult a dermatologist before using turmeric on your skin. The best way to prevent an allergic reaction from occurring is to test the product on a small area of skin, such as the forearm, 24 to 48 hours in advance. If it causes a rash, avoid using it on your face.
It may slow blood clotting in people with bleeding disorders
Recent studies suggest that curcumin, an ingredient in turmeric, can inhibit platelet aggregation and dissolve clots. In addition, turmeric has other health benefits, including modulating blood sugar and cholesterol levels. Taking turmeric on a regular basis can reduce the risk of cardiovascular complications and other conditions. This herb is popular in India because it can help stop bleeding from fresh cuts. It also contains proteases, enzymes essential for blood clotting.
Although turmeric may slow blood clotting in people with various conditions, it may not be the best choice for people with bleeding disorders. It is best to follow a doctor’s advice before taking turmeric supplements. Patients should be monitored for any adverse effects, including bleeding and stroke. Moreover, turmeric should be avoided in those who have bleeding disorders and those on blood-thinning medications. Although turmeric’s anti-platelet properties seem promising, more human studies are needed to confirm its effectiveness.
It may reduce itching in people with long-term kidney disease
The chemical curcumin found in turmeric may help treat inflammatory skin conditions. It is also effective at reducing pain and fatigue after surgeries. People with chronic kidney disease may also find turmeric useful for reducing blood pressure and itching. In addition, it can help those with Crohn’s disease and ulcerative colitis, as well as people who have undergone bypass surgery. Turmeric also helps to reduce liver toxicity caused by antituberculosis therapy.
In a recent study, researchers at the University of Bristol in the United Kingdom found that turmeric can reduce itching associated with chronic kidney disease, especially in people who have chronic itching. However, it is important to note that this type of itch is different from allergic itching. People who suffer from chronic kidney disease may want to consult a doctor before taking any medications or other treatments. The use of these medicines may increase the risk of side effects and should be limited.